I'm broadly interested in physiology with specific focuses on endocrinology, neurobiology and reproduction.
I am interested in research aimed at improving human health.
My current research projects focus on using mouse behavior as a model for human health. Using this approach, I am currently focused on establishing a mouse model of autistic-like behavior. I recently authored a grant that was funded through the National Institutes of Health to further my research on mouse behavior and its relevance to autism.
I have also used rodent behavior to study the endocrine disrupting potential of pharmaceutical and plastic pollutants. My most recent publication in this field was selected as a ‘Research Highlight' by the journal Toxicological Sciences.
Principles of Biology
Biology of Life for non-majors
1996 – 1999: Science Instructor, Gaston Day School
1999 – 2005: Predoctoral Research Assistant, North Carolina State University
2005 – 2006: Postdoctoral Research Fellow, Joint Appointment in the Reproductive Toxicology Division, EB, NHEERL, United States Environmental Protection Agency and the Curriculum in Toxicology, University of North Carolina
2006 – 2008: Postdoctoral Research Fellow, Neurodevelopmental Disorders Research Center, University of North Carolina
NIMH Grant 1R21MH084132-01A1 awarded in 2008 to characterize a novel mouse model of restricted, repetitive behavior.
BC Ryan, AK Hotchkiss, KL Howdeshell, KM Crofton, LE Gray (2009). In utero and Lactational Exposure to Bisphenol A, in contrast to Ethinyl Estradiol, Does not Alter Sexually Dimorphic Behavior, Puberty, Fertility and Anatomy of Female LE Rats. Toxicological Sciences. Epub ahead of print. doi:10.1093/toxsci/kfp266
BC Ryan, NB Young, SS Moy, JN Crawley (2008). Olfactory Cues are Sufficient to Elicit Social Approach Behaviors but not Social Transmission of Food Preference in C57BL/6J Mice. Behavioural Brain Research. 193:235-242. doi:10.1016/j.bbr.2008.06.002
KL Howdeshell, J Furr, CR Lambright, VS Wilson, BC Ryan, LE Gray (2007). Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male Long Evans hooded rat. Toxicological Sciences. 102:371-382. doi:10.1093/toxsci/kfm306
CV Owens, C Lambright, K Bobseine, B Ryan, LE Gray, BK Gullett, VS Wilson (2007). Identification of estrogenic compounds emitted from the combustion of computer printed circuit boards in electronic waste. Environmental Science and Technology. 41:8506-8511. doi:10.1021/es071425p
CR Blystone, J Furr, CS Lambright, KL Howdeshell, BC Ryan, VS Wilson, GA LeBlanc, LE Gray (2007). Prochloraz inhibits testosterone production at dosage below those that affect androgen-dependent organ weights or the onset of puberty in the male Sprague Dawley rat. Toxicological Sciences. 97:65-74. doi:10.1093/toxsci/kfm004
BC Ryan and JG Vandenbergh (2006). Developmental exposure to environmental estrogens alters adult behavior in the mouse. Hormones and Behavior. 50:85-93. doi:10.1016/j.yhbeh.2006.01.007
BC Ryan and JG Vandenbergh (2002). Intrauterine position effects. Neuroscience and Biobehavioral Reviews. 26:665-678. doi:10.1016/S0149-7634(02)00038-6
Member – American Physiological Society